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Evf2 (Dlx6as) lncRNA regulates ultraconserved enhancer methylation and the differential transcriptional control of adjacent genes

Several lines of evidence suggest that long non-coding RNA (lncRNA)-dependent mechanisms regulate transcription and CpG DNA methylation. Whereas CpG island methylation has been studied in detail, the significance of enhancer DNA methylation and its relationship with lncRNAs is relatively unexplored....

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Detalhes bibliográficos
Main Authors: Berghoff, Emily G., Clark, Mary F., Chen, Sean, Cajigas, Ivelisse, Leib, David E., Kohtz, Jhumku D.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007716/
https://ncbi.nlm.nih.gov/pubmed/24089468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.099390
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