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Chemical-Genetics of Rapamycin-Insensitive TORC2 in S. cerevisiae

Current approaches for identifying synergistic targets use cell culture models with combinations of clinically available drugs to see if the combined effect of the combination is better than predicted by their individual efficacy. New techniques are needed to systematically and rationally identify t...

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Bibliografische gegevens
Hoofdauteurs: Kliegman, Joseph I., Fiedler, Dorothea, Ryan, Colm J., Xu, Yi-Fan, Su, Xiao-yang, Thomas, David, Caccese, Max C., Cheng, Ada, Shales, Michael, Rabinowitz, Joshua D., Krogan, Nevan J., Shokat, Kevan M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007695/
https://ncbi.nlm.nih.gov/pubmed/24360963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.040
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