A novel polymer-lipid hybrid nanoparticle for efficient nonviral gene delivery

AIM: To develop a novel non-viral vector with high transfection efficiency and low cytotoxicity. METHODS: Poly (ethylene glycol)-distearoylphosphatidylethanolamine (PEG-DSPE) was incorporated into polymer-lipid hybrid nanoparticles (PLN) to construct a PEG-DSPE modified long circulating PLN (L-PLN)....

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Bibliographic Details
Main Authors: Li, Jian, He, Ying-zi, Li, Wen, Shen, Yun-zhen, Li, Yu-ru, Wang, Yun-feng
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007669/
https://ncbi.nlm.nih.gov/pubmed/20348944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.15
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