Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

BACKGROUND: The bacterial ribosome is a primary target of several classes of antibiotics. Investigation of the structure of the ribosomal subunits in complex with different antibiotics can reveal the mode of inhibition of ribosomal protein synthesis. Analysis of the interactions between antibiotics...

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Bibliographic Details
Main Authors: Harms, Jörg M, Schlünzen, Frank, Fucini, Paola, Bartels, Heike, Yonath, Ada
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC400760/
https://ncbi.nlm.nih.gov/pubmed/15059283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-2-4
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