Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

BACKGROUND: The bacterial ribosome is a primary target of several classes of antibiotics. Investigation of the structure of the ribosomal subunits in complex with different antibiotics can reveal the mode of inhibition of ribosomal protein synthesis. Analysis of the interactions between antibiotics...

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Detalles Bibliográficos
Publicado en:BMC Biol
Main Authors: Harms, Jörg M, Schlünzen, Frank, Fucini, Paola, Bartels, Heike, Yonath, Ada
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2004
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15059283/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1741-7007-2-4
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