SHEAR: sample heterogeneity estimation and assembly by reference

BACKGROUND: Personal genome assembly is a critical process when studying tumor genomes and other highly divergent sequences. The accuracy of downstream analyses, such as RNA-seq and ChIP-seq, can be greatly enhanced by using personal genomic sequences rather than standard references. Unfortunately,...

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Main Authors: Landman, Sean R, Hwang, Tae Hyun, Silverstein, Kevin AT, Li, Yingming, Dehm, Scott M, Steinbach, Michael, Kumar, Vipin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
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Software
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007568/
https://ncbi.nlm.nih.gov/pubmed/24476358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-84
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