Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines

Persistent androgen receptor (AR) transcriptional activity underlies resistance to AR-targeted therapy and progression to lethal castration resistant prostate cancer (CRPC). Recent success in re-targeting persistent AR activity with next-generation androgen/AR axis inhibitors such as enzalutamide (M...

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Hlavní autoři: Li, Yingming, Chan, Siu Chiu, Brand, Lucas J., Hwang, Tae Hyun, Silverstein, Kevin A. T., Dehm, Scott M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549016/
https://ncbi.nlm.nih.gov/pubmed/23117885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3630
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