Matrine induces caspase-independent program cell death in hepatocellular carcinoma through bid-mediated nuclear translocation of apoptosis inducing factor

Matrine, a clinical drug in China, has been used to treat viral hepatitis, cardiac arrhythmia and skin inflammations. Matrine also exhibits chemotherapeutic potential through its ability to trigger cancer cell death. However, the mechanisms involved are still largely unknown. The objective of this s...

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Bibliographic Details
Main Authors: Zhou, Huan, Xu, Minying, Gao, Ya, Deng, Zhigang, Cao, Hanwei, Zhang, Wenqing, Wang, Qiao, Zhang, Bing, Song, Gang, Zhan, Yanyan, Hu, Tianhui
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007561/
https://ncbi.nlm.nih.gov/pubmed/24628719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-59
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