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Ancient and Recent Selective Pressures Shaped Genetic Diversity at AIM2-Like Nucleic Acid Sensors
AIM2-like receptors (ALRs) are a family of nucleic acid sensors essential for innate immune responses against viruses and bacteria. We performed an evolutionary analysis of ALR genes (MNDA, PYHIN1, IFI16, and AIM2) by analyzing inter- and intraspecies diversity. Maximum-likelihood analyses indicated...
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Main Authors: | , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Oxford University Press
2014
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007548/ https://ncbi.nlm.nih.gov/pubmed/24682156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evu066 |
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