Ancient and Recent Selective Pressures Shaped Genetic Diversity at AIM2-Like Nucleic Acid Sensors

AIM2-like receptors (ALRs) are a family of nucleic acid sensors essential for innate immune responses against viruses and bacteria. We performed an evolutionary analysis of ALR genes (MNDA, PYHIN1, IFI16, and AIM2) by analyzing inter- and intraspecies diversity. Maximum-likelihood analyses indicated...

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Bibliographic Details
Main Authors: Cagliani, Rachele, Forni, Diego, Biasin, Mara, Comabella, Manuel, Guerini, Franca R., Riva, Stefania, Pozzoli, Uberto, Agliardi, Cristina, Caputo, Domenico, Malhotra, Sunny, Montalban, Xavier, Bresolin, Nereo, Clerici, Mario, Sironi, Manuela
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007548/
https://ncbi.nlm.nih.gov/pubmed/24682156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evu066
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