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OASes and STING: Adaptive Evolution in Concert
OAS (2′–5′-oligoadenylate synthases) proteins and cyclic GMP–AMP synthase (cGAS, gene symbol: MB21D1) patrol the cytoplasm for the presence of foreign nucleic acids. Upon binding to double-stranded RNA or double-stranded DNA, OAS proteins and cGAS produce nucleotide second messengers to activate RNa...
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| Pubblicato in: | Genome Biol Evol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419793/ https://ncbi.nlm.nih.gov/pubmed/25752600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv046 |
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