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Gene Family Level Comparative Analysis of Gene Expression in Mammals Validates the Ortholog Conjecture
The ortholog conjecture (OC), which is central to functional annotation of genomes, posits that orthologous genes are functionally more similar than paralogous genes at the same level of sequence divergence. However, a recent study challenged the OC by reporting a greater functional similarity, in t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007545/ https://ncbi.nlm.nih.gov/pubmed/24610837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evu051 |
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