SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells

BACKGROUND: SMAD4 is a gastrointestinal malignancy-specific tumor suppressor gene found mutated in one third of colorectal cancer specimens and half of pancreatic tumors. SMAD4 inactivation by allelic deletion or intragenic mutation mainly occurs in the late stage of human pancreatic ductal adenocar...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Yu-Wen, Hsiao, Pi-Jung, Weng, Ching-Chieh, Kuo, Kung-Kai, Kuo, Tzu-Lei, Wu, Deng-Chyang, Hung, Wen-Chun, Cheng, Kuang-Hung
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007528/
https://ncbi.nlm.nih.gov/pubmed/24625091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-181
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