Evidence for Steric Regulation of Fibrinogen Binding to Staphylococcus aureus Fibronectin-binding Protein A (FnBPA)

The adjacent fibrinogen (Fg)- and fibronectin (Fn)-binding sites on Fn-binding protein A (FnBPA), a cell surface protein from Staphylococcus aureus, are implicated in the initiation and persistence of infection. FnBPA contains a single Fg-binding site (that also binds elastin) and multiple Fn-bindin...

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Autors principals: Stemberk, Vaclav, Jones, Richard P. O., Moroz, Olga, Atkin, Kate E., Edwards, Andrew M., Turkenburg, Johan P., Leech, Andrew P., Massey, Ruth C., Potts, Jennifer R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007472/
https://ncbi.nlm.nih.gov/pubmed/24627488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.543546
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