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Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains

Staphylococcus aureus can adhere to and invade endothelial cells by binding to the human protein fibronectin (Fn). FnBPA and FnBPB, cell wall-attached proteins from S. aureus, have multiple, intrinsically disordered, high-affinity binding repeats (FnBRs) for Fn. Here, 30 years after the first report...

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Detalhes bibliográficos
Main Authors: Bingham, Richard J., Rudiño-Piñera, Enrique, Meenan, Nicola A. G., Schwarz-Linek, Ulrich, Turkenburg, Johan P., Höök, Magnus, Garman, Elspeth F., Potts, Jennifer R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518095/
https://ncbi.nlm.nih.gov/pubmed/18713862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803556105
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