Transcription of Angiogenin and Ribonuclease 4 Is Regulated by RNA Polymerase III Elements and a CCCTC Binding Factor (CTCF)-dependent Intragenic Chromatin Loop

Angiogenin (ANG) and ribonuclease 4 (RNASE4), two members of the secreted and vertebrate-specific ribonuclease superfamily, play important roles in cancers and neurodegenerative diseases. The ANG and RNASE4 genes share genetic regions with promoter activities, but the structure and regulation of the...

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Bibliographische Detailangaben
Hauptverfasser: Sheng, Jinghao, Luo, Chi, Jiang, Yuxiang, Hinds, Philip W., Xu, Zhengping, Hu, Guo-fu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007445/
https://ncbi.nlm.nih.gov/pubmed/24659782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.551762
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