A Novel Small-molecule Tumor Necrosis Factor α Inhibitor Attenuates Inflammation in a Hepatitis Mouse Model

Overexpression of tumor necrosis factor α (TNFα) is a hallmark of many inflammatory diseases, including rheumatoid arthritis, inflammatory bowel disease, and septic shock and hepatitis, making it a potential therapeutic target for clinical interventions. To explore chemical inhibitors against TNFα a...

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Detalhes bibliográficos
Main Authors: Ma, Li, Gong, Haiyan, Zhu, Haiyan, Ji, Qing, Su, Pei, Liu, Peng, Cao, Shannan, Yao, Jianfeng, Jiang, Linlin, Han, Mingzhe, Ma, Xiaotong, Xiong, Dongsheng, Luo, Hongbo R., Wang, Fei, Zhou, Jiaxi, Xu, Yuanfu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007440/
https://ncbi.nlm.nih.gov/pubmed/24634219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521708
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