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Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis
Usher syndrome (USH), the leading cause of hereditary combined hearing and vision loss, is characterized by sensorineural deafness and progressive retinal degeneration. Mutations in several different genes produce USH, but the proximal cause of sensory cell death remains mysterious. We adapted a pro...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Limited
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007406/ https://ncbi.nlm.nih.gov/pubmed/24626987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.014068 |
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