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Tracing ancestry with methylation patterns: most crypts appear distantly related in normal adult human colon

BACKGROUND: The ability to discern ancestral relationships between individual human colon crypts is limited. Widely separated crypts likely trace their common ancestors to a time around birth, but closely spaced adult crypts may share more recent common ancestors if they frequently divide by fission...

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Detalhes bibliográficos
Main Authors: Kim, Kyoung-Mee, Shibata, Darryl
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400737/
https://ncbi.nlm.nih.gov/pubmed/15059289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-4-8
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