Lactate dehydrogenase 5 isoenzyme overexpression defines resistance of prostate cancer to radiotherapy

BACKGROUND: Radiotherapy provides high-cure rates in prostate cancer. Despite its overall slow clinical growth, high proliferation rates documented in a subset of tumours relate to poor radiotherapy outcome. This study examines the role of anaerobic metabolism in prostate cancer growth and resistanc...

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Detalhes bibliográficos
Main Authors: Koukourakis, M I, Giatromanolaki, A, Panteliadou, M, Pouliliou, S E, Chondrou, P S, Mavropoulou, S, Sivridis, E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007238/
https://ncbi.nlm.nih.gov/pubmed/24714743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.158
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