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Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility

Atopic dermatitis can result from loss of structural proteins in the outermost epidermal layers, leading to a defective epidermal barrier. To test whether this influences tumour formation, we chemically induced tumours in EPI−/− mice, which lack three barrier proteins—Envoplakin, Periplakin, and Inv...

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Detaylı Bibliyografya
Asıl Yazarlar: Cipolat, Sara, Hoste, Esther, Natsuga, Ken, Quist, Sven R, Watt, Fiona M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007207/
https://ncbi.nlm.nih.gov/pubmed/24843010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01888
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