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Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility
Atopic dermatitis can result from loss of structural proteins in the outermost epidermal layers, leading to a defective epidermal barrier. To test whether this influences tumour formation, we chemically induced tumours in EPI−/− mice, which lack three barrier proteins—Envoplakin, Periplakin, and Inv...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007207/ https://ncbi.nlm.nih.gov/pubmed/24843010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01888 |
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