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A novel de novo duplication mutation of PAX6 in a Chinese family with aniridia and other ocular abnormalities

Aniridia is a congenital panocular disorder caused by the mutations of the paired box gene-6 (PAX6). To investigate the clinical characterization and the underlying genetic defect in a Chinese family with aniridia and other ocular abnormalities, we recruited the family members who underwent ophthalm...

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Détails bibliographiques
Auteurs principaux: Zhuang, Jianfu, Chen, Xiaole, Tan, Zhihua, Zhu, Yihua, Zhao, Kanxing, Yang, Juhua
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007070/
https://ncbi.nlm.nih.gov/pubmed/24787241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04836
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