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Protein Scaffold-Activated Protein Trans-Splicing in Mammalian Cells

Conditional protein splicing is a powerful biotechnological tool that can be used to rapidly and post-translationally control the activity of a given protein. Here we demonstrate a novel conditional splicing system in which a genetically encoded protein scaffold induces the splicing and activation o...

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Hlavní autoři: Selgrade, Daniel F., Lohmueller, Jason J., Lienert, Florian, Silver, Pamela A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006946/
https://ncbi.nlm.nih.gov/pubmed/23621664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja401689b
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