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Activation of Lung Toll-like Receptors Does Not Exacerbate Sickness Responses to Lipopolysaccharide in Mice

Pneumonia represents a leading cause of death. Recently, a novel treatment strategy for pneumonia has involved enhancing the host pulmonary innate immune response by pre-exposure to aerosolized toll-like receptor (TLR)9 and TLR2/6 agonists, known as O/P. O/P inhalation in mice has been demonstrated...

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Detalhes bibliográficos
Main Authors: Walker, Adam K., Hsieh, Jennifer, Luu, Katherine V., Radwan, Aiat, Valverde, Gabriella R., Dickey, Burton F., Tuvim, Michael J., Dantzer, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006945/
https://ncbi.nlm.nih.gov/pubmed/24534636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2014.02.004
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