Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response

Substance P (neurokinin-1 [NK1]) receptor antagonists appear to be effective antidepressant and anxiolytic agents, as indicated in 3 double-blind clinical trials. In laboratory animals, they promptly attenuate the responsiveness of serotonin (5-hydroxytryptamine [5-HT]) and norepinephrine (NE) neuro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Blier, Pierre, Gobbi, Gabriella, Haddjeri, Nasser, Santarelli, Luca, Mathew, Gina, Hen, René
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2004
Pynciau:
CRSN Symposium
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC400690/
https://ncbi.nlm.nih.gov/pubmed/15173897
Tagiau: Ychwanegu Tag
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