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Chemotherapy engages multiple pathways leading to IL-1β production by myeloid leukocytes

Interleukin-1β (IL-1β) can limit tumor growth by promoting T cell-mediated antitumor immune responses. Several chemotherapeutic agents can stimulate the production of IL-1β by tumor-infiltrating leukocytes via the NLRP3 inflammasome. We have recently demonstrated that some chemotherapeutics can also...

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Detalhes bibliográficos
Main Authors: Antonopoulos, Christina, Dubyak, George R
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006851/
https://ncbi.nlm.nih.gov/pubmed/24800164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27499
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