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Deletion of the Nuclear Localization Sequences and C-Terminus of PTHrP Impairs Embryonic Mammary Development but also Inhibits PTHrP Production

Parathyroid hormone-related protein (PTHrP) can be secreted from cells and interact with its receptor, the Type 1 PTH/PTHrP Receptor (PTHR1) in an autocrine, paracrine or endocrine fashion. PTHrP can also remain inside cells and be transported into the nucleus, where its functions are unclear, altho...

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Bibliografische gegevens
Hoofdauteurs: Boras-Granic, Kata, Dann, Pamela, VanHouten, Joshua, Karaplis, Andrew, Wysolmerski, John
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006745/
https://ncbi.nlm.nih.gov/pubmed/24785493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090418
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