Increased PTHrP and Decreased Estrogens Alter Bone Turnover but Do Not Reproduce the Full Effects of Lactation on the Skeleton

During lactation, calcium is mobilized from the maternal skeleton to supply the breast for milk production. This results in rapid but fully reversible bone loss. Prior studies have suggested that PTHrP, secreted from the breast, and estrogen deficiency, due to suckling-induced central hypogonadism,...

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Hlavní autoři: Ardeshirpour, Laleh, Brian, Susan, Dann, Pamela, VanHouten, Joshua, Wysolmerski, John
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999486/
https://ncbi.nlm.nih.gov/pubmed/21047946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0566
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