An In Vivo EGF Receptor Localization Screen in C. elegans Identifies the Ezrin Homolog ERM-1 as a Temporal Regulator of Signaling

The subcellular localization of the epidermal growth factor receptor (EGFR) in polarized epithelial cells profoundly affects the activity of the intracellular signaling pathways activated after EGF ligand binding. Therefore, changes in EGFR localization and signaling are implicated in various human...

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Detalhes bibliográficos
Main Authors: Haag, Andrea, Gutierrez, Peter, Bühler, Alessandra, Walser, Michael, Yang, Qiutan, Langouët, Maeva, Kradolfer, David, Fröhli, Erika, Herrmann, Christina J., Hajnal, Alex, Escobar-Restrepo, Juan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006739/
https://ncbi.nlm.nih.gov/pubmed/24785082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004341
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