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PTEN Negatively Regulates MAPK Signaling during Caenorhabditis elegans Vulval Development
Vulval development in Caenorhabditis elegans serves as an excellent model to examine the crosstalk between different conserved signaling pathways that are deregulated in human cancer. The concerted action of the RAS/MAPK, NOTCH, and WNT pathways determines an invariant pattern of cell fates in three...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3420937/ https://ncbi.nlm.nih.gov/pubmed/22916028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002881 |
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