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PTEN Negatively Regulates MAPK Signaling during Caenorhabditis elegans Vulval Development

Vulval development in Caenorhabditis elegans serves as an excellent model to examine the crosstalk between different conserved signaling pathways that are deregulated in human cancer. The concerted action of the RAS/MAPK, NOTCH, and WNT pathways determines an invariant pattern of cell fates in three...

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Bibliografske podrobnosti
Main Authors: Nakdimon, Itay, Walser, Michael, Fröhli, Erika, Hajnal, Alex
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420937/
https://ncbi.nlm.nih.gov/pubmed/22916028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002881
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