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Determining Effects of Non-synonymous SNPs on Protein-Protein Interactions using Supervised and Semi-supervised Learning

Single nucleotide polymorphisms (SNPs) are among the most common types of genetic variation in complex genetic disorders. A growing number of studies link the functional role of SNPs with the networks and pathways mediated by the disease-associated genes. For example, many non-synonymous missense SN...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhao, Nan, Han, Jing Ginger, Shyu, Chi-Ren, Korkin, Dmitry
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006705/
https://ncbi.nlm.nih.gov/pubmed/24784581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003592
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