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Molecular signatures of virulence in the PB1-F2 proteins of H5N1 influenza viruses
The PB1-F2 protein of influenza A viruses contributes to pathogenesis in animal models. Specific molecular signatures of virulence within PB1-F2 have been mapped for some functions. The 66S polymorphism may modulate interferon activity, and four C-terminal amino acids, 62L, 75R, 79R, and 82L, contri...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006689/ https://ncbi.nlm.nih.gov/pubmed/23499672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2013.02.012 |
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