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Effect of 1918 PB1-F2 Expression on Influenza A Virus Infection Kinetics

Relatively little is known about the viral factors contributing to the lethality of the 1918 pandemic, although its unparalleled virulence was likely due in part to the newly discovered PB1-F2 protein. This protein, while unnecessary for replication, increases apoptosis in monocytes, alters viral po...

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Hlavní autoři: Smith, Amber M., Adler, Frederick R., McAuley, Julie L., Gutenkunst, Ryan N., Ribeiro, Ruy M., McCullers, Jonathan A., Perelson, Alan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040654/
https://ncbi.nlm.nih.gov/pubmed/21379324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001081
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