High K(+)-induced contraction requires depolarization-induced Ca(2+) release from internal stores in rat gut smooth muscle

AIM: Depolarization-induced contraction of smooth muscle is thought to be mediated by Ca(2+) influx through voltage-gated L-type Ca(2+) channels. We describe a novel contraction mechanism that is independent of Ca(2+) entry. METHODS: Pharmacological experiments were carried out on isolated rat gut l...

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Bibliographische Detailangaben
Hauptverfasser: Kirschstein, Timo, Rehberg, Mirko, Bajorat, Rika, Tokay, Tursonjan, Porath, Katrin, Köhling, Rüdiger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006678/
https://ncbi.nlm.nih.gov/pubmed/19578389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.98
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