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Over-expression of NYGGF4 inhibits glucose transport in 3T3-L1 adipocytes via attenuated phosphorylation of IRS-1 and Akt

AIM: NYGGF4 is a novel gene that is abundantly expressed in the adipose tissue of obese patients. The purpose of this study was to investigate the effects of NYGGF4 on basal and insulin-stimulated glucose uptake in mature 3T3-L1 adipocytes and to understand the underlying mechanisms. METHODS: 3T3-L1...

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Bibliografiske detaljer
Main Authors: Zhang, Chun-mei, Chen, Xiao-hui, Wang, Bin, Liu, Feng, Chi, Xia, Tong, Mei-ling, Ni, Yu-hui, Chen, Rong-hua, Guo, Xi-rong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006536/
https://ncbi.nlm.nih.gov/pubmed/19079291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2008.9
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