Calcineurin/NFAT pathway mediates wear particle-induced TNF-α release and osteoclastogenesis from mice bone marrow macrophages in vitro

AIM: To investigate the roles of the calcineurin/nuclear factor of activated T cells (NFAT) pathway in regulation of wear particles-induced cytokine release and osteoclastogenesis from mouse bone marrow macrophages in vitro. METHODS: Osteoclasts were induced from mouse bone marrow macrophages (BMMs)...

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Main Authors: Liu, Feng-xiang, Wu, Chuan-long, Zhu, Zhen-an, Li, Mao-qiang, Mao, Yuan-qing, Liu, Ming, Wang, Xiao-qing, Yu, De-gang, Tang, Ting-ting
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006473/
https://ncbi.nlm.nih.gov/pubmed/24056707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.99
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