A pro-invasive role for the Ca(2+)-activated K(+) channel KCa3.1 in malignant glioma

Glioblastoma multiforme (GBM) are highly motile primary brain tumors. Diffuse tissue invasion hampers surgical resection leading to poor patient prognosis. Recent studies suggest that intracellular Ca(2+) acts as a master regulator for cell motility and engages a number of downstream signals includi...

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Bibliographic Details
Main Authors: Turner, Kathryn L., Honasoge, Avinash, Robert, Stephanie M., McFerrin, Michael M., Sontheimer, Harald
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006152/
https://ncbi.nlm.nih.gov/pubmed/24585442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22655
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