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A pro-invasive role for the Ca(2+)-activated K(+) channel KCa3.1 in malignant glioma
Glioblastoma multiforme (GBM) are highly motile primary brain tumors. Diffuse tissue invasion hampers surgical resection leading to poor patient prognosis. Recent studies suggest that intracellular Ca(2+) acts as a master regulator for cell motility and engages a number of downstream signals includi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006152/ https://ncbi.nlm.nih.gov/pubmed/24585442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22655 |
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