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mTOR signaling and its roles in normal and abnormal brain development

Target of rapamycin (TOR) was first identified in yeast as a target molecule of rapamycin, an anti-fugal and immunosuppressant macrolide compound. In mammals, its orthologue is called mammalian TOR (mTOR). mTOR is a serine/threonine kinase that converges different extracellular stimuli, such as nutr...

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Detalhes bibliográficos
Main Authors: Takei, Nobuyuki, Nawa, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005960/
https://ncbi.nlm.nih.gov/pubmed/24795562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00028
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