HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification

The recent HIV-1 vaccine failures highlight the need to better understand virus-host interactions. One key question is why CD8(+) T cell responses to two HIV-Gag regions are uniquely associated with delayed disease progression only in patients expressing a few rare HLA class I variants when these re...

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Autori principali: Tenzer, Stefan, Crawford, Hayley, Pymm, Phillip, Gifford, Robert, Sreenu, Vattipally B., Weimershaus, Mirjana, de Oliveira, Tulio, Burgevin, Anne, Gerstoft, Jan, Akkad, Nadja, Lunn, Daniel, Fugger, Lars, Bell, John, Schild, Hansjörg, van Endert, Peter, Iversen, Astrid K.N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005910/
https://ncbi.nlm.nih.gov/pubmed/24726370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.031
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