Vaccinia virus GLV-1h153 in combination with (131)I shows increased efficiency in treating triple-negative breast cancer

We investigated the therapeutic efficacy of a replication-competent oncolytic vaccinia virus, GLV-1h153, carrying human sodium iodide symporter (hNIS), in combination with radioiodine in an orthotopic triple-negative breast cancer (TNBC) murine model. In vitro viral infection was confirmed by immuno...

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Detalhes bibliográficos
Main Authors: Gholami, Sepideh, Chen, Chun-Hao, Lou, Emil, Belin, Laurence J., Fujisawa, Sho, Longo, Valerie A., Chen, Nanhai G., Gönen, Mithat, Zanzonico, Pat B., Szalay, Aladar A., Fong, Yuman
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005795/
https://ncbi.nlm.nih.gov/pubmed/24186964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-237222
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