An Oncolytic Vaccinia Virus Expressing the Human Sodium Iodine Symporter Prolongs Survival and Facilitates SPECT/CT Imaging in an Orthotopic Model of Malignant Pleural Mesothelioma

BACKGROUND: The purpose of this original work is to examine the ability of an oncolytic vaccinia virus expressing the human sodium iodine transporter (hNIS) to provide real time monitoring of viral therapy and effective treatment of malignant pleural mesothelioma (MPM). METHODS: Infectivity and cyto...

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Main Authors: Belin, Laurence J., Ady, Justin W., Lewis, Christina, Marano, Drew, Gholami, Sepideh, Mojica, Kelly, Eveno, Clarisse, Longo, Valerie, Zanzonico, Pat B., Chen, Nanhai G., Szalay, Aladar A., Fong, Yuman
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123996/
https://ncbi.nlm.nih.gov/pubmed/23890748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2013.06.004
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