Abortive T Follicular Helper Development Is Associated with a Defective Humoral Response in Leishmania infantum-Infected Macaques

Leishmania infantum causes a chronic infectious disease named visceral leishmaniasis (VL). We employed a non-human primate model to monitor immune parameters over time and gain new insights into the disease. Rhesus macaques were infected with L. infantum and the T helper and B cell immunological pro...

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Autores principales: Rodrigues, Vasco, Laforge, Mireille, Campillo-Gimenez, Laure, Soundaramourty, Calaiselvy, Correia-de-Oliveira, Ana, Dinis-Oliveira, Ricardo Jorge, Ouaissi, Ali, Cordeiro-da-Silva, Anabela, Silvestre, Ricardo, Estaquier, Jérôme
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005728/
https://ncbi.nlm.nih.gov/pubmed/24763747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004096
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