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Transcript level and sequence determinants of protein abundance and noise in Escherichia coli

The range over which a protein is expressed, and its cell-to-cell variability, is often thought to be linked to the demand for its activity. Steady-state protein level is determined by multiple mechanisms controlling transcription and translation, many of which are limited by DNA- and RNA-encoded si...

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Détails bibliographiques
Auteurs principaux: Guimaraes, Joao C., Rocha, Miguel, Arkin, Adam P.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005695/
https://ncbi.nlm.nih.gov/pubmed/24510099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku126
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