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Functional Genomic Analysis of Fluconazole Susceptibility in the Pathogenic Yeast Candida glabrata: Roles of Calcium Signaling and Mitochondria
The pathogenic yeast Candida glabrata exhibits innate resistance to fluconazole, the most commonly used antifungal agent. By screening a library of 9,216 random insertion mutants, we identified a set of 27 genes which upon mutation, confer altered fluconazole susceptibility in C. glabrata. Homologue...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2004
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC400560/ https://ncbi.nlm.nih.gov/pubmed/15105111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1600-1613.2004 |
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