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Fluconazole‐induced actin cytoskeleton remodeling requires phosphatidylinositol 3‐phosphate 5‐kinase in the pathogenic yeast Candida glabrata
Known azole antifungal resistance mechanisms include mitochondrial dysfunction and overexpression of the sterol biosynthetic target enzyme and multidrug efflux pumps. Here, we identify, through a genetic screen, the vacuolar membrane‐resident phosphatidylinositol 3‐phosphate 5‐kinase (CgFab1) to be...
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| Gepubliceerd in: | Mol Microbiol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6221164/ https://ncbi.nlm.nih.gov/pubmed/30137648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14110 |
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