Novel Polysulfated Galactose-Derivatized Dendrimers as Binding Antagonists of Human Immunodeficiency Virus Type 1 Infection

Evidence indicates that galactosyl ceramide (GalCer) and its 3′-sulfated derivative, sulfatide (SGalCer), may act as alternate coreceptors for human immunodeficiency virus type 1 (HIV-1) in CD4(−) cells. Glycosphingolipids (GSLs) may also be necessary for fusion of HIV-1 and host cell membranes. Usi...

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Main Authors: Kensinger, Richard D., Catalone, Bradley J., Krebs, Fred C., Wigdahl, Brian, Schengrund, Cara-Lynne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400553/
https://ncbi.nlm.nih.gov/pubmed/15105112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1614-1623.2004
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