Influence of βS-globin haplotypes hydroxyurea on tumor necrosis factor-alpha levels in sickle cell anemia

BACKGROUND: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha. Hydroxyurea, by decreasing the polymerization of hemoglobin, reduces inflammatory states. The effect of the genetic polymorphi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Laurentino, Marília Rocha, Filho, Pedro Aurio Maia, Barbosa, Maritza Cavalcante, Bandeira, Izabel Cristina Justino, da Silva Rocha, Lilianne Brito, Gonçalves, Romelia Pinheiro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Sociedade Brasileira de Hematologia e Hemoterapia 2014
Pynciau:
Original article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005510/
https://ncbi.nlm.nih.gov/pubmed/24790537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20140028
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