Clinical Strains of Pseudomonas aeruginosa Overproducing MexAB-OprM and MexXY Efflux Pumps Simultaneously

Simultaneous overexpression of the MexAB-OprM and MexXY efflux systems was demonstrated by real-time reverse transcription-PCR and immunoblotting experiments for 12 multiresistant clinical isolates of Pseudomonas aeruginosa. DNA sequencing analysis showed that nine of these strains (named agrZ mutan...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Llanes, Catherine, Hocquet, Didier, Vogne, Christelle, Benali-Baitich, Dounia, Neuwirth, Catherine, Plésiat, Patrick
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400543/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15105137/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.5.1797-1802.2004
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