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Novel Modeling of Cancer Cell Signaling Pathways Enables Systematic Drug Repositioning for Distinct Breast Cancer Metastases

A new type of signaling network element, called cancer signaling bridges (CSB), has been shown to have the potential for systematic and fast-tracked drug repositioning. On the basis of CSBs, we developed a computational model to derive specific downstream signaling pathways that reveal previously un...

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Autors principals: Zhao, Hong, Jin, Guangxu, Cui, Kemi, Ren, Ding, Liu, Timothy, Chen, Peikai, Wong, Solomon, Li, Fuhai, Fan, Yubo, Rodriguez, Angel, Chang, Jenny, Wong, Stephen TC
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005386/
https://ncbi.nlm.nih.gov/pubmed/24097821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4617
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